Ndidi and Iwobi have enjoyed contrasting fortunes at their respective clubs this season and both will look to hog the headlines for the right reasons at the end of the contest.
Leicester City occupy second position in the Premier League table with Ndidi already one of the key performers for the Foxes.
The 22-year-old has formed a formidable partnership with Youri Tielemans and James Maddison in the middle of the pack.
Ndodi has also contributed two goals in 12 league appearances for Brendan Rodgers’ men this season.
Iwobi’s Everton have struggled to make an impact in Premier League this season and a win in this game will no doubt ease pressure on manager Marco Silva.
The Toffees sit in 16th position in the table, just four points above the relegation zone.
Iwobi has made 11 league appearances for Everton this season with a goal to his name.