Real Madrid took the lead through Brazilian forward Rodrygo in the 53rd minute.
The home team however equalised two minutes later with Dennis setting up Hans Vanaken for the goal.
The visitors however scored two goals in the second half through Vinicius Junior and Luca Modric to win the game.
It would be recalled that Dennis scored a brace in Brugge’s 2-2 away draw against Real Madrid on matchday-one.
Dennis’ international teammate, David Okereke was an unused substitute for Club Brugge in the game.
Dennis has now featured in 10 Champions League games for Club Brugge this season and scored three goals.
Okereke on the other has made eight appearances for the club.
Brugge will now feature in the UEFA Europa League after they finished third in the group.
At the Estadio Wanda Metropolitano, Bryan Idowu was in action for 90 minutes in Locomotiv Moscow’s
2-0 away defeat to Atletico Madrid.
It was Idowu’s fourth appearance in the competition for Locomotiv Moscow this season.
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